Knowing about rapid weight loss in older women, what does the heart say

Australia: Unexplained rapid weight loss in older people could be a sign of underlying disease and can be linked with an increased risk of falls and fractures, as well as a poorer long-term prognosis. The understanding of factors that could contribute to rapid weight loss remains poor, with current treatments including correcting suboptimal dietary and physical activity behaviors.

New research by Edith Cowan University (ECU) Postdoctoral Research Fellow Dr Cassandra Smith noted that abdominal aortic calcification (AAC), a marker of advanced blood vessel disease, was linked to higher risk of rapid weight loss in the 929 older women who participated in the study

Rapid weight loss is defined as a more than five percent decrease in body weight within any 12-month interval over five years of observations. “Rapid weight loss, when it occurs in older women can be a sign of bad things to come such as early institutionalisation, cognitive decline, Alzheimer’s disease, and pose a higher risk for falls and fractures,” Dr Smith said.

During a five-year observation, 39.4 percent of the patients had rapid weight loss, which was associated with a 49 percent increase in the risk of dying in the next 9.5 years. This risk of dying increased to 87 percent in women who experienced rapid weight loss of more than ten percent in a 12-month interval.