Polypill Shows LDL Lowering Advantage in High risk Primary Prevention Patients
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Cardiovascular polypills are important as a fixed-dose combination of medications with proven benefits for the prevention of cardiovascular disease by combining different drug classes in a single pill to simultaneously target more than one risk factor.
Whether the treatment with the CNIC-polypill was at least non-inferior to usual care in terms of low-density lipoprotein cholesterol (LDL-c) and systolic BP (SBP) values in subjects at high or very high risk without a previous cardiovascular event. The switch from conventional treatment to the CNIC-polypill approach in patients at high Cardiovascular risk without a previous event was safe and appears a reasonable strategy to control risk factors and prevent cardiovascular diseases.
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