Premature Coronary Artery Disease- Know it all
Written By : Dr. Nandita Mohan
Medically Reviewed By : Dr. Kamal Kant Kohli
Published On 2022-08-25 03:30 GMT | Update On 2022-08-25 03:30 GMT
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Premature coronary artery disease (CAD) is an endemic in India. Researchers performed a study to identify risk factors, clinical presentation, angiographic findings and interventions in premature coronary artery disease.
Successive patients who underwent percutaneous intervention (PCI) accounting for a total of 1238 patients and very premature in 212 patients. In premature and very premature vs non-premature coronary artery disease, cholesterol, non-HDL cholesterol, LDL cholesterol and tobacco use were higher while hypertension, diabetes and chronic kidney disease were more in non-premature class. Presentation as STEMI was marginally more in women with premature and very premature coronary artery disease and was significantly higher in men.
So the researchers concluded that in a country like ours, a third of coronary artery disease patients presenting for coronary intervention have premature disease. Important risk factors are high total and non-HDL cholesterol and tobacco (men). Extent and type of coronary artery disease are similar to non-premature coronary artery disease indicating severe disease.
Reference: Sanjeev K. Sharma, Jitender S. Makkar, et al; Premature Coronary Artery Disease, Risk Factors, Clinical Presentation, Angiography and Interventions: Hospital Based Registry, Indian Heart Journal, DOI: https://doi.org/10.1016/j.ihj.2022.08.003.
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