Study Links Childhood Cavities and Gum Disease to Greater Adult Heart Disease Risk

A recent study published in the International Journal of Cardiology has found that poor oral health in childhood may be linked to a higher risk of developing atherosclerotic cardiovascular disease (ASCVD) later in life. ASCVD is a major contributor to premature mortality worldwide and includes conditions such as ischemic heart disease, myocardial infarction, and ischemic stroke. Because cardiovascular disease often develops gradually over decades, identifying early-life risk factors is important for improving prevention strategies.

Oral diseases such as dental caries, gingivitis, and periodontitis are common in children and can trigger chronic inflammation in the body. Inflammation and the spread of oral bacteria into the bloodstream have been proposed as potential mechanisms linking oral disease to cardiovascular problems. However, most previous research has focused on oral health in adults, leaving the long-term impact of childhood oral health less explored.

To address this gap, researchers conducted a nationwide Danish cohort study using national health registry data from more than 568,000 individuals aged 30 years or older. Childhood dental records from the National Child Odontology Registry were used to classify participants according to the presence and severity of dental caries and gingivitis during childhood.

The findings showed that individuals who experienced persistently poor or worsening oral health during childhood had a significantly higher risk of developing ASCVD later in life. Severe dental caries in childhood was associated with a 32% higher risk of ASCVD in males and a 45% higher risk in females. Similarly, severe gingivitis increased ASCVD risk by 21% in males and 31% in females.

Although the study does not establish a direct causal relationship, it highlights the potential long-term health implications of childhood oral disease. The researchers suggest that improving dental care and oral hygiene in early life could contribute to reducing future cardiovascular disease risk and improving overall long-term health outcomes.

REFERENCE: Nygaard, N., D’Aiuto, F., Eriksen, A. K., et al. (2026). Childhood oral health is associated with the incidence of atherosclerotic cardiovascular disease in adulthood. International Journal of Cardiology. DOI: https://doi.org/10.1016/j.ijcard.2025.134151.