Tralokinumab, topical corticosteroids combination beneficial in Atopic dermatitis

Published On 2021-11-09 12:11 GMT   |   Update On 2021-11-09 12:11 GMT
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Atopic dermatitis (AD), is a common chronic or recurrent inflammatory skin disease and affects 15-20% of children and 1-3% of adults worldwide. Cyclosporine A (CSA) is a popularly used in AD, but treatment with CSA has potentially serious adverse effects. A phase 3 trial Capsinoids plus topical corticosteroids (TCS) as needed provided early and sustained improvements in AD signs and symptoms.

A randomized trial by J. Gutermuth and team revealed that tralokinumab 300 mg plus topical corticosteroids as needed was effective and well tolerated in patients with severe AD not adequately controlled with oral corticosteroids or who had contraindications to them.

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Tralokinumab Plus Topical Corticosteroids Effective In Severe Atopic Dermatitis

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