Consumption of fruits as last meal reduces fasting blood sugar independent of DPP4 activity

 A randomized pilot study published in the Journal of Obesity has shown the effects of the combination of a fruit-carbohydrate meal sequence and 2 min of postprandial exercise on DPP4 activity and blood sugar levels in type 2 diabetes mellitus (T2DM) patients.

The study found that the consumption of fruit as the last meal reduced the level of fasting blood sugar, while the consumption of fruits as the first meal did not remarkably reduce the one-hour postprandial blood sugar (1 h PP sugar) level. Postprandial exercise addition lowered DPP4 activity; however, both treatments had no acute effects on the action.

"The preliminary report of fruits meal sequence is plausibly involved in the acute regulation of blood sugar levels and might be independent of dipeptidyl peptidase 4 (DPP4) activity in Indonesian T2DM patients. Postprandial exercise through the mediation of DPP4 may be an important intervention for T2DM but did not acutely affect the regulation of blood glucose levels," Indarto Dono and colleagues from Indonesia wrote in their study.

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Consumption Of Fruits As Last Meal Reduces Fasting Blood Sugar Independent Of DPP4 Activity