Benefits of ginseng, ginkgo, and saffron extracts for Memory Function

A recent study has shown that SaiLuoTong (SLT) supplementation, a herbal supplement that contains extracts including ginseng, ginkgo and crocus sativus (saffron), demonstrated significant improvements in delayed memory retrieval and executive function in individuals with mild cognitive impairment (MCI) while being well-tolerated, offering potential support for cognitive health in this population. This research focused on community-dwelling people aged 60 years or older and offers promising insights into the power of SLT.

In this study, 78 participants with MCI were randomly assigned to receive either 180 mg/day of SLT or a placebo for a duration of 12 weeks. The findings reveal significant improvements in various cognitive domains. After the 12-week period, the participants who received SLT demonstrated a remarkable difference in their cognitive performance compared to the placebo group.

Specifically, they exhibited significant improvements in Logical Memory delayed recall scores, Delis–Kaplan Executive Function System Trail Making Test Condition 4 switching and contrast scaled scores, Rey Auditory Verbal Learning Test delayed recall, and Functional Activities Questionnaire.

The improvements were striking, with differences ranging from 1.21 to 1.56, demonstrating that SLT had a notable impact on memory retrieval and executive function in individuals with MCI. Importantly, the study also confirmed that SLT is well tolerated in individuals aged 60 and above.

Reference: A randomized, double-blind, placebo-controlled, parallel-group 12-week pilot phase II trial of SaiLuoTong (SLT) for cognitive function in older adults with mild cognitive impairment, Genevieve Z. Steiner-Lim et al, 11 October 2023 https://doi.org/10.1002/trc2.12420