Menopause: HRT linked to depression
The findings of this study of women in Denmark followed up from age 45 suggest that systemically administered (oral or transdermal) hormonal therapy before and during menopause is associated with higher risk of depression, especially in the years immediately after initiation, whereas locally administered (intravaginal or intrauterine) hormonal therapy is associated with lower risk of depression for women 54 years or older.
Reference :
Wium-Andersen, M. K., MD PhD,DMSc1; Terese S. H. Jørgensen, MSc, PhD1,2; Anniken H. Halvorsen, BSc1; et al, (2022, November 1, Association of Hormone Therapy With Depression During Menopause in a Cohort of Danish Women, Depressive Disorders, JAMA Network Open, 2022;5(11):e2239491, doi:10.1001/jamanetworkopen.2022.39491
Disclaimer: This website is primarily for healthcare professionals. The content here does not replace medical advice and should not be used as medical, diagnostic, endorsement, treatment, or prescription advice. Medical science evolves rapidly, and we strive to keep our information current. If you find any discrepancies, please contact us at corrections@medicaldialogues.in. Read our Correction Policy here. Nothing here should be used as a substitute for medical advice, diagnosis, or treatment. We do not endorse any healthcare advice that contradicts a physician's guidance. Use of this site is subject to our Terms of Use, Privacy Policy, and Advertisement Policy. For more details, read our Full Disclaimer here.
NOTE: Join us in combating medical misinformation. If you encounter a questionable health, medical, or medical education claim, email us at factcheck@medicaldialogues.in for evaluation.