Medical Bulletin 10/December/2021

Published On 2021-12-10 10:39 GMT   |   Update On 2021-12-10 10:41 GMT
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Chondroitin sulfate reliable treatment for diabetic osteoporosis

A new study by Shan Shan Qi and the team revealed chondroitin sulfate could prevent streptozotocin (STZ)-induced diabetic osteoporosis (DOP) and repair bone microstructure. The main mechanism is through regulating bone metabolism, anti-oxidation, and anti-inflammatory. The findings of the study, published in the
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Frontiers in Endocrinology,
indicate that chondroitin sulfate could be used for the development of anti-DOP functional foods and diet interventions for diabetes.
The results showed that chondroitin sulfate can reduce blood sugar and relieve symptoms in diabetic rats. In addition, it can significantly increase bone mineral density, reduce bone marrow adipocyte number in diabetic rats, and improve bone microstructure. After 10 weeks of chondroitin sulfate administration, the SOD activity level was upregulated, as well as CAT levels, indicating that chondroitin sulfate can alleviate oxidative stress in diabetic rats.
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Chondroitin Sulfate Reliable Treatment For Diabetic Osteoporosis: Study


Postural orthostatic tachycardia syndrome related to small bowel hypo-contractility pattern

 According to a new study done by Wendy Zhou and colleagues, motility problems in postural orthostatic tachycardia syndrome (POTS) patients appear to impact mostly the small intestine and demonstrate a general hypo-contractility pattern. In individuals with POTS and GI symptoms, a wireless motility capsule might possibly aid guide treatment. The findings of this study were published in the journal Digestive Diseases and Sciences on 11th January 2021.

Postural orthostatic tachycardia syndrome is an autonomic disorder that affects multiple organs, including the gastrointestinal system. These patients often have complaints of multiple GI problems with a severe impact on their quality of life.

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Postural Orthostatic Tachycardia Syndrome Related To Small Bowel Hypo-Contractility Pattern: Study


Vitamin D involvement in cognition of Multiple Sclerosis

In past decades, cognitive impairment (CI) was underestimated in multiple sclerosis (MS) patients and thought to appear only in primary progressive (PP) and secondary progressive (SP) disease stages. Presently, it is well established that CI affects a large proportion of MS patients from onset to all disease stages. In a recent study, researchers have found that low vitamin D levels worsen both cognition and early disability in newly diagnosed MS patients. The study findings were published in the journal Brain Sciences on November 17, 2021.

Few studies explored the possible correlation between CI and vitamin D in the MS population. However, studies on vitamin D supplementation so far have not included cognitive evaluation, Although vitamin D and cognitive impairment in other neurodegenerative diseases have already been linked. Therefore, Dr Eleonora Virgilio and her team conducted a study to explore the possible correlation between vitamin D and cognition, particularly information processing speed (IPS), early in the disease, precisely at MS diagnosis, using the Symbol Digit Modalities Test (SDMT).

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Study Finds Vitamin D Involvement In Cognition Of Multiple Sclerosis


New antidiabetic treatment approved for human trials

A new anti-diabetic compound derived from a garden flower has been approved by Health Canada for Phase 1 human trials. GlycoNet researcher Stephen Withers anticipates that the compound could be used to develop a treatment with fewer side effects than other options currently available to those with Type 2 diabetes.

"Our approach is to slow down the degradation of the starch component of your food, but not affect the simple sugars," says Withers, lead researcher and professor at the University of British Columbia (UBC).

For more details, check out the full story in link below:

New Anti-Diabetic Treatment Approved For Human Trials 

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