Medical Bulletin 14/December/2021

Here are Top Medical news for the day

Tapinarof cream effective for patients with plaque psoriasis

Findings from two identical phase 3 trials showed the once-daily application of tapinarof 1% cream to be superior to vehicle control in reducing plaque psoriasis severity over a period of 12 weeks. However, the cream was associated with local adverse events and headaches. The study appears in the New England Journal of Medicine.

The authors stress the need for larger and longer trials for evaluating the safety and efficacy of tapinarof cream versus existing treatments for psoriasis.

For more details, check out the full story on the link below:

Tapinarof Cream Effective For Patients With Plaque Psoriasis: Study

Severe COVID could reduce male fertility

Each day, clinicians and scientists are learning more about the acute and long-term health effects of COVID-19 on the body. A new study from the University of Georgia explores the potential impact of the virus on male fertility.

The article, published recently in Nature Reviews Urology, reviews the ways SARS-CoV-2 might target and infect testicular cells. The authors also provide an experimental framework for tracking how the virus could impact testicular function and fertility in acute COVID-19 patients.

For more details, check out the full story on the link below:

Severe COVID Could Reduce Male Fertility, Finds Study

Melatonin may exacerbate asthma leading to nocturnal symptoms

Patients with asthma often experience a worsening of asthmatic symptoms at night in so-called "nocturnal asthma." According to reports, more than 50% of asthma deaths occur at night, exposing a link between nocturnal asthma symptoms and asthma deaths. Although some have proposed several triggers that explain the pathogenesis of nocturnal asthma, the precise mechanisms regulating this asthma phenotype remain obscure.

Now, a research group led by Kentaro Mizuta from Tohoku University Graduate School of Dentistry has discovered that melatonin, a sleep hormone, worsens asthma.

For more details, check out the full story on the link below:

Melatonin May Exacerbate Asthma Leading To Nocturnal Symptoms, Finds Study

Lupus a harmful trigger for macular degeneration

Researchers at the University of Virginia School of Medicine have made a discovery linking lupus, a potentially debilitating autoimmune disorder, and macular degeneration, a leading cause of blindness.

The two diseases share a common contributor to harmful inflammation, the scientists found. The insights could let researchers develop new treatments for those diseases and other conditions driven by the newly discovered inflammation source.

For more details, check out the full story on the link below:

Lupus A Harmful Trigger For Macular Degeneration, Finds Study