Top Medical Bulletin 3/June/2022

Here are the top health stories for today:

Cardiac surgery in infective endocarditis with ICH linked to brain deterioration?  

according to a recent study published in the Journal of the American Heart Association, Cardiac surgery within 30 days in infective endocarditis with intracranial haemorrhage was not associated with higher mortality,rather with an increased rate of neurological deterioration.

The researchers evaluated the impact of early surgery in patients with infective endocarditis (IE) with Intracranial haemorrhage (ICH) on postoperative neurological deterioration and all‐cause mortality.

For more information check out the full story on the link below:

Cardiac surgery in infective endocarditis with ICH linked to brain deterioration? 

Congenital heart defects among mothers increase heart defect risk in children    

previous smaller studies have already reported a higher offspring risk for mothers with congenital heart defects, or Congenital heart defects. But researchers of the present study wanted to confirm those findings in a larger population and also delve into specific cardiac defects. So as per this new research, Congenital heart defects may be much more common among children of women with heart defects than of men with heart defects.

They looked at more than 2 million children and compared the risk of congenital heart defects in children with and without a parent with a Congenital heart defects.

For more information check out the full story on the link below: 

Congenital heart defects among mothers increase heart defect risk in children

 Metformin improves antibacterial treatment speed    

Old dogs may not learn new tricks, but old drugs can. according to a research team based in China. A collaboration found that Metformin, a small molecule drug that has been used to treat type II diabetes for more than 50 years, can improve the efficiency and efficacy of antibacterial treatments for quick wound-healing. The results were published in Nano Research journal.

The abuse of antibiotics has led to serious bacterial resistance, with about 1.27 million deaths in 2019 due to multidrug-resistant bacterial infections, bacterial resistance poses a fatal threat to human health. Non-antibiotic antibacterial technologies and antibacterial nanoagents with specific catalytic activities not only produce toxic substrates to directly kill bacteria-including antibiotic-resistant bacteria-but can also reduce the risk of the bacteria developing resistance to drugs.

For more information check out the full story on the link below:

Metformin improves antibacterial treatment speed

 Gut bacteria inactivates certain BP medicines leading to resistant hypertension       

A new study from The University of Toledo College of Medicine and Life Sciences has shown gut bacteria can reduce the effectiveness of certain blood pressure drugs.

The research, published in the journal Hypertension, offers the first clues to what has been an elusive mystery-why do some people not respond well to medication? High blood pressure is often called a silent killer because it doesn't usually cause symptoms. However, there is a big population of individuals who know they have hypertension but still cannot get it under control, even though they're taking blood pressure drugs thereby causing a major concern.

For more information check out the full story on the link below:

Gut bacteria inactivates certain BP medicines leading to resistant hypertension