Launched in 1977, the WHO Model Lists serve as a critical global policy tool for guiding the selection and coverage of essential medicines, particularly in public procurement and insurance systems. The 24th edition of the EML and the 10th edition of the EMLc were informed by a rigorous review of 59 applications, including 31 proposals for new medicine inclusions. As a result, 20 new medicines were added to the EML and 15 to the EMLc, bringing the total to 523 medicines for adults and 374 for children.
Cancer continues to be a major global health burden, and the updated EML reflects a stronger emphasis on therapies that show significant clinical benefit. Pembrolizumab was added to the EML as a first-line monotherapy for metastatic cervical cancer, metastatic colorectal cancer, and metastatic non-small cell lung cancer. For the latter, atezolizumab and cemiplimab are included as therapeutic alternatives. The Expert Committee backed strategies to optimize dosage and implement reforms aimed at improving cancer treatment access, especially in low-resource settings.
Diabetes and obesity treatments were another key focus. GLP-1 receptor agonists—semaglutide, dulaglutide, liraglutide—and the dual receptor agonist tirzepatide were added based on robust evidence of improved outcomes in patients with type 2 diabetes and comorbidities. “Achieving equitable access to essential medicines requires a coherent health system response backed by strong political will, multisectoral cooperation, and people-centred programmes that leave no one behind,” said Deusdedit Mubangizi, WHO Director of Policy and Standards for Medicines and Health Products.
The updated lists underscore WHO’s commitment to global health equity by identifying cost-effective, clinically proven treatments with the greatest potential public health impact.
Reference: https://www.who.int/news/item/05-09-2025-who-updates-list-of-essential-medicines-to-include-key-cancer--diabetes-treatments
Disclaimer: This website is primarily for healthcare professionals. The content here does not replace medical advice and should not be used as medical, diagnostic, endorsement, treatment, or prescription advice. Medical science evolves rapidly, and we strive to keep our information current. If you find any discrepancies, please contact us at corrections@medicaldialogues.in. Read our Correction Policy here. Nothing here should be used as a substitute for medical advice, diagnosis, or treatment. We do not endorse any healthcare advice that contradicts a physician's guidance. Use of this site is subject to our Terms of Use, Privacy Policy, and Advertisement Policy. For more details, read our Full Disclaimer here.
NOTE: Join us in combating medical misinformation. If you encounter a questionable health, medical, or medical education claim, email us at factcheck@medicaldialogues.in for evaluation.