Phytochemicals May Aid Neurological Disorder Treatment by Impacting Gut-Brain Axis: Study
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In a recent study published in the journal Current Developments in Nutrition, researchers explored the potential therapeutic implications of phytochemicals on the gut-brain axis (GBA).
The gut-brain axis (GBA) connects the enteric and central nervous systems through neurological, immunological, and hormonal pathways. Changes in gut microbiota and their metabolites are linked to neurological disorders like anxiety, autism, depression, migraine, multiple sclerosis, and Parkinson's disease.
Dietary polyphenols like curcumin, coumarins, cinnamic acid, lignans, and flavonoids can modulate gut microbiota and improve blood-brain barrier (BBB) permeability. Gut microbiota enzymes transform polyphenols into smaller compounds with better absorption.
Phytochemicals can regulate the GBA by interacting with the immune system, neurotransmitters, and gut microbiota, potentially improving brain function. Certain evidence suggests that phytochemicals might be an effective treatment for neurological disorders.
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