Study Sheds Light on Common Medications' Hidden Impact on Brain Development through Unexpected Cholesterol Disruption
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In a peer-reviewed Perspective (review) article, researchers at the University of Nebraska Medical Center have uncovered concerning evidence that commonly prescribed medications may interfere with crucial brain development processes by disrupting sterol biosynthesis. Their findings, published in Brain Medicine suggest that this previously overlooked mechanism could have significant implications for medication safety during pregnancy and early development.
"What we've discovered is that many prescription medications, while designed for entirely different purposes, can inadvertently interfere with the brain's ability to produce and process sterols, including cholesterol," explains Professor Károly Mirnics, lead author of the review. "This is particularly concerning because the brain requires precise sterol regulation for proper development and function."
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