Journal Club-Are maternal psychological stress and insulin resistance during pregnancy interrelated?
Various physiological mechanisms counteract insulin resistance (IR) during normal pregnancy. Psychological stress is a known, independent risk factor for developing insulin resistance. Pregnancy-specific psychological stress may cause insulin resistance and increase the risk of overt diabetes. Hence, the present study that I am talking about today aimed to evaluate maternal psychological stress using multiple stress markers and also understand their association with changes in insulin resistance during pregnancy and postpartum.
The researchers measured the anthropometric measurements such as height, weight and skinfold thickness using standard techniques. The stress markers were assessed among fifty healthy pregnant women during pregnancy and postpartum using perceived stress scales, a physiological marker of stress and biochemical stress markers. Insulin resistance was estimated using homeostasis model assessment-estimated IR (HOMA-IR).
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