Study Finds Potential Link Between Endometriosis and Ovarian Cancer
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A recent study published in JAMA revealed that women with ovarian endometriomas or deep infiltrating endometriosis face a significantly heightened risk of developing ovarian cancer.
Endometriosis affects approximately 11% of reproductive-aged women, including 50% to 60% of women and teenage girls experiencing pelvic pain and up to 50% of women with infertility. This condition has been associated with various comorbidities, including ovarian, breast, and endometrial cancers, and impacts mental, menstrual, urinary, bowel, and other nonspecific symptoms.
The study, conducted using data from the Utah Population Database (UPDB), aimed to evaluate the association between endometriosis and ovarian cancer incidence. Researchers developed a retrospective cohort, including women aged 18 to 55 years with at least one diagnosis of endometriosis.
The findings revealed an observed endometriosis prevalence of 6.3%, with categories including superficial peritoneal endometriosis, ovarian endometriomas, deep infiltrating endometriosis, ovarian endometriosis, and concurrent deep infiltrating endometriosis. Women with a history of endometriosis were matched 1:5 with unexposed women.
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