Electrical signals between skin cells may affect melanoma initiation, shows study
Written By : Isra Zaman
Medically Reviewed By : Dr. Kamal Kant Kohli
Published On 2023-08-14 04:00 GMT | Update On 2023-08-14 04:00 GMT
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The transfer of a neurotransmitter from one type of skin cell to another (melanocytes to keratinocytes) altered electrical activity and promoted melanoma initiation in preclinical models, according to results published in Cancer Discovery. An intrinsic feature of melanocytes is their ability to secrete melanin-containing vesicles to surrounding skin cells called keratinocytes to give skin its color. While approximately half of all melanomas harbor mutations in the BRAF gene, these mutations are present in many benign skin lesions as well.
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