For resistant breast cancers, two drugs may be better than one
Cancer cells are even smarter than scientists previously believed, according to new CU Boulder research. When these cells are confronted with potent new drugs called CDK2 inhibitors, which are designed to prevent cancer from proliferating, they can trigger a workaround to survive the assault in as little as one to two hours.
But the study, published June 8 in the journal “Cell,” comes with a silver lining. It reveals how cancer cells complete this adaption and shows that simultaneously administering a second, the already widely available drug may hobble cancer cells and shrink resistant tumors. The findings bolster the idea, which is currently under investigation in at least three clinical trials, that when it comes to treating resistant breast cancer, two drugs may be better than one.
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