Research Finds Novel Mechanism That Predicts Severity Of Triple Negative Breast Cancer
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Scientists at Huntsman Cancer Institute at the University of Utah (the U), the National Cancer Institute-designated cancer centre for the Mountain West, have made a significant breakthrough in predicting the prognosis of triple-negative breast cancer (TNBC), a particularly aggressive disease.
Their research, published in JCO Precision Oncology as part of the TOWARDS study, has led to the development of a new mechanism that accurately forecasts the aggressiveness of triple-negative breast cancer. This advancement could revolutionize the way doctors treat triple-negative breast cancer, allowing them to identify higher-risk patients and tailor precise treatments.
Currently, triple-negative breast cancer lacks reliable methods to predict recurrence after treatments like chemotherapy and surgery. Unlike other breast cancers, triple-negative breast cancer is challenging to treat because its tumour cells lack estrogen receptors, progesterone receptors, and high levels of HER2/neu protein, according to experts at the National Institutes of Health. This often results in a higher likelihood of relapse after treatment.
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