Increased alcohol consumption poses a risk factor for geographic atrophy in eye

Published On 2021-12-16 07:45 GMT | Update On 2021-12-16 11:38 GMT

Age-related macular degeneration (AMD) is a leading cause of blindness in Western countries. Advanced AMD consists of geographic atrophy (GA) and neovascular AMD (nAMD). Treatment is currently only available for nAMD and comes in the form of intravitreal injections of anti–vascular endothelial growth factor. This treatment is invasive, expensive, of limited effectiveness, and poses a considerable burden on patients. Therefore, increased public health efforts need to be directed toward prevention of advanced AMD. Identifying causal, modifiable risk factors for advanced AMD is critical to implementing interventions for prevention.

Mendelian randomization (MR) is a technique that has been used to assess potential causal associations across a wide range of diseases. MR is based on the principle that if a genetic variant causes a change in an exposure (eg, smoking or alcohol intake), and if this exposure is causal for a disease (eg, advanced AMD), then the genetic variant should also be associated with risk of the disease. Valerie Kuan and team used MR to assess the potential causal role of other exposures that are amenable to intervention (ie, smoking, alcohol intake, bodymass index [BMI], blood pressure, and glycemic traits) on the risk of advanced AMD and its subtypes, GA and nAMD, using publicly available data.

For more details, check out the full story on the link below:

Increased Alcohol Intake Causal Risk Factor For Geographic Atrophy In Eye: JAMA

Full View

Disclaimer: This website is primarily for healthcare professionals. The content here does not replace medical advice and should not be used as medical, diagnostic, endorsement, treatment, or prescription advice. Medical science evolves rapidly, and we strive to keep our information current. If you find any discrepancies, please contact us at corrections@medicaldialogues.in. Read our Correction Policy here. Nothing here should be used as a substitute for medical advice, diagnosis, or treatment. We do not endorse any healthcare advice that contradicts a physician's guidance. Use of this site is subject to our Terms of Use, Privacy Policy, and Advertisement Policy. For more details, read our Full Disclaimer here.

NOTE: Join us in combating medical misinformation. If you encounter a questionable health, medical, or medical education claim, email us at factcheck@medicaldialogues.in for evaluation.

Dr. Nandita Mohan

Dr. Nandita Mohan is a practicing pediatric dentist with more than 5 years of clinical work experience. Along with this, she is equally interested in keeping herself up to date about the latest developments in the field of medicine and dentistry which is the driving force for her to be in association with Medical Dialogues. She also has her name attached with many publications; both national and international. She has pursued her BDS from Rajiv Gandhi University of Health Sciences, Bangalore and later went to enter her dream specialty (MDS) in the Department of Pedodontics and Preventive Dentistry from Pt. B.D. Sharma University of Health Sciences. Through all the years of experience, her core interest in learning something new has never stopped. She can be contacted at editorial@medicaldialogues.in. Contact no. 011-43720751

Comments Policy

Our comments section is governed by our Comments Policy . By posting comments at Medical Dialogues you automatically agree with our Comments Policy , Terms And Conditions and Privacy Policy .

Increased alcohol consumption poses a risk factor for geographic atrophy in eye

Similar News

Can Just an Hour of Scrolling Reels Lead to Eye Strain? Study Provides Insights

Surgical Implant Slows Vision Loss in Rare Eye Disease: NEJM Evidence Study

WHO Issues Safety Over Rare Eye Disorder from Semaglutide Use

Diabetes and Weight-Loss Drug Semaglutide Linked to Rare Eye Condition: European Medical Agency

Fear of Vision Loss May Delay Cataract Surgery: Study Finds

BRESER Study Demonstrates Real-World Efficacy and Safety of Lupin's Ranibizumab Biosimilar (Ranieyes)

Screen Time Surge: Digital Devices Linked to Rising Nearsightedness, Study Finds

Pioneering Retinal-Surgery Robot from University of Utah Shows Early Promise