PPIs use to cause fracture risk in rheumatoid arthritis

Published On 2022-02-03 11:20 GMT | Update On 2022-02-03 11:20 GMT

Rheumatoid arthritis is an auto immune disorder that causes pain, swelling, stiffness and loss of function in your joints. It can affect any joint but is common in the wrist and fingers. This greatly affects ones quality of life.

Concomitant use of PPIs and oral glucocorticoids increases risk of osteoporotic fractures by 1.6-fold in rheumatoid arthritis (RA) patients (aged 50 years and above), finds a recent study. The results of the study, published in the BMJ journal Annals of the Rheumatic Diseases, suggests that fracture risk assessment should be considered when a RA patient is prescribed both oral GCs and PPIs.

Rheumatoid arthritis patients commonly use proton pump inhibitors (PPIs) and oral glucocorticoids (GCs) both of which are associated with osteoporotic fractures. Shahab Abtahi, Maastricht University Medical Centre, Maastricht, The Netherlands, and colleagues investigated the association between concomitant use of oral GCs and PPIs and osteoporotic fractures risk among RA patients.

For more information check out the full story on the link below:

PPI, oral glucocorticoids use linked to fracture risk in rheumatoid arthritis patients: BMJ

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Dr. Nandita Mohan

Dr. Nandita Mohan is a practicing pediatric dentist with more than 5 years of clinical work experience. Along with this, she is equally interested in keeping herself up to date about the latest developments in the field of medicine and dentistry which is the driving force for her to be in association with Medical Dialogues. She also has her name attached with many publications; both national and international. She has pursued her BDS from Rajiv Gandhi University of Health Sciences, Bangalore and later went to enter her dream specialty (MDS) in the Department of Pedodontics and Preventive Dentistry from Pt. B.D. Sharma University of Health Sciences. Through all the years of experience, her core interest in learning something new has never stopped. She can be contacted at editorial@medicaldialogues.in. Contact no. 011-43720751

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PPIs use to cause fracture risk in rheumatoid arthritis

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