Ferric Citrate Hydrate Shows High Efficacy and Tolerability in Treating Iron Deficiency Anemia: Study
Japan: Researchers have found in a recent multicenter, open-label, single-arm study that Ferric citrate hydrate (FCH) treatment achieved an 80% hemoglobin target success rate by week 4 in patients with iron deficiency anemia (IDA). The study highlighted that FCH demonstrated better tolerability and compliance, primarily due to a reduced risk of gastrointestinal side effects, leading to a high medication completion rate among patients.
The study, conducted across multiple centers in Japan and published in Advances in Therapy, was led by Dr. Osamu Wada-Hiraike from the Department of Obstetrics and Gynecology at the University of Tokyo. It specifically focused on women with IDA who had previously experienced nausea and vomiting after using conventional oral iron supplements.
A total of 30 Japanese female participants who had difficulty tolerating previous iron therapies were enrolled. Each received 500 mg of FCH orally per day, with some extending to 1,000 mg/day based on clinical need. Patients with hemoglobin levels ≥11.0 g/dL completed the treatment at four weeks, while those below that threshold continued up to eight weeks.
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