Just 12 minutes of intense exercise significantly improves metabolic health: Study
BOSTON -Regular exercise is associated with lower risk of cardiovascular disease and mortality but mechanisms of exercise-mediated health benefits remain less clear.
Researchers at Massachusetts General Hospital (MGH) have found in a new study that short bursts of physical exercise induce changes in the body's levels of metabolites that correlate to, and may help gauge, an individual's cardiometabolic, cardiovascular and long-term health.
In a paper published in Circulation, the research team describes how approximately 12 minutes of acute cardiopulmonary exercise impacted more than 80% of circulating metabolites, including pathways linked to a wide range of favorable health outcomes, thus identifying potential mechanisms that could contribute to a better understanding of cardiometabolic benefits of exercise.
"Much is known about the effects of exercise on cardiac, vascular and inflammatory systems of the body, but our study provides a comprehensive look at the metabolic impact of exercise by linking specific metabolic pathways to exercise response variables and long-term health outcomes," says investigator Gregory Lewis, MD, section head of Heart Failure at MGH and senior author of the study. "What was striking to us was the effects a brief bout of exercise can have on the circulating levels of metabolites that govern such key bodily functions as insulin resistance, oxidative stress, vascular reactivity, inflammation and longevity."
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