Physical activity helps curb low-grade inflammation and chronic diseases in children

"Our study showed that children who were physically more active and less sedentary had a healthier inflammatory profile than children who were physically less active," explains Dr. Eero Haapala from the Faculty of Sport and Health Sciences at the University of Jyväskylä. "However, our results suggest that the positive effects of high levels of vigorous physical activity and low levels of sedentary time on low-grade inflammation are partly explained by their positive effects on body composition."

Low physical activity, unhealthy diet quality, and being overweight is the most unfavourable combination

Researchers found unhealthier inflammatory profile particularly in children with the lowest levels of physical activity, poorest diet quality and the highest body fat percentage.

"The key message of our results is that increasing physical activity and reducing sedentary time are key in preventing low-grade inflammation since childhood," says Haapala. "They would be particularly important for overweight children."

The study looked at the associations between physical activity, sedentary time, diet quality, body fat content, and low-grade inflammation in 390 children aged 6 to 8 years. Physical activity and sedentary time were measured by a combined heart rate and movement sensor and body composition with a DXA device. Low-grade inflammation was assessed using biomarkers measured from blood samples.