Baseline Kidney Function Predicts Mortality in Crush Syndrome Post-Earthquake: Study
Researchers have found in a new study that pre-earthquake kidney function is a significant predictor of mortality in patients with crush syndrome, emphasizing the need for baseline renal assessment as part of disaster preparedness and emergency medical planning.
The study published in BMC Nephrology sheds light on the critical role of pre-disaster kidney function in determining survival outcomes for patients with earthquake-related crush syndrome. Conducted by Dr. Ramazan Daniş and colleagues from Gazi Yasargil Educational Research Hospital in Diyarbakır, Türkiye, the research focused on victims of the devastating February 2023 Kahramanmaraş earthquakes.
The study aimed to assess whether kidney function before the earthquake could serve as a reliable predictor of in-hospital mortality among those affected by crush syndrome, a serious condition caused by prolonged compression of muscles, often leading to acute kidney injury (AKI).
Using a multi-center, retrospective design, the researchers evaluated medical records from 469 patients across 46 nephrology clinics. Information on kidney function before the earthquake—measured through serum creatinine and estimated glomerular filtration rate (eGFR)—was retrieved from existing health records. Additional clinical and laboratory parameters, including complications and survival data, were also analyzed. Multivariate Cox regression was used to identify factors independently linked to patient mortality.
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