Low vitamin B12 levels associated with primary monosymptomatic nocturnal enuresis: Study
A new study published in the Journal of Pediatric Urology found that children who have low or borderline vitamin B12 levels are more prone to experience primary monosymptomatic nocturnal enuresis (PMNE).
Urinary control systems may be impacted by micronutrient deficits, especially those involving vitamin B12. The most prevalent voiding issue in the pediatric population is PMNE, which is defined as involuntary nighttime urination in children past the age at which bladder control would typically be expected. Over the past few decades, nocturnal enuresis has continued to be the subject of substantial scientific inquiry due to its high incidence. Despite much discussion, the etiology of PNE is still not fully known.
Although their precise functions in both healthy and diseased settings are not entirely understood, vitamin B12 and folate are crucial for the metabolism, growth, and maturation of the nervous system. Despite a great deal of study on PNE, there are still a lot of concerns about its precise pathogenesis. Thus, this study wanted to determine whether vitamin B12 insufficiency is a possible risk factor for the development of enuresis and to examine the association between children's blood vitamin B12 levels and PMNE.
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