Hyperkalemia treated with medical management vs hemodialysis leads to comparable results: Study
Hyperkalemia managed with medical management vs hemodialysis (HD) gives comparable results, according to a recent study presented at Kidney Week 2021, a virtual meeting of the American Society of Nephrology.
Hyperkalemia is a life-threatening electrolyte disorder for which there exists a paucity of data regarding the benefit of urgent hemodialysis over medical management. Researchers hypothesized there would be no difference in potassium levels among hyperkalemic patients who received only medical management compared to those who received hemodialysis, without hemodialysis.
This is a retrospective study of patients 18+ years old with hyperkalemia (K > 5.5mmol/L). One group (medical management, or MM) had medication(s)—including insulin/dextrose, sodium zirconium cyclosilicate, sodium polystyrene sulfonate, calcium gluconate, albuterol, or furosemide—ordered within 3h of initial elevated potassium. The other group (hemodialysis, or HD), had hemodialysis ordered—with or without medical management—within 3h of elevated potassium. The initial potassium level was considered "time-zero" and subsequent timepoints were followed up to 100h. T1 readings were established between 0–3 hours; T6: 3–8h; T12: 8–16h; T24: 20–28h; T48: 40–56h; T72: 60–100h.
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