Increased Physical Activity Linked to Lower Mortality in Peritoneal Dialysis Patients: Study
Researchers have found in a new retrospective observational cohort study that among patients undergoing peritoneal dialysis, incremental increases in physical activity were associated with a 31% reduction in all-cause mortality risk. Higher overall activity levels and longer daily walking durations correlated with better clinical outcomes, highlighting physical activity as a potentially important and modifiable factor for improving survival in this patient population.
Studies have identified physical inactivity as an important modifiable risk factor for mortality, morbidity, and reduced quality of life in chronic kidney disease patients. Physical activity and patients prognosis has been widely studied in patients with chronic kidney disease or under hemodialysis therapy. However, this association remains unclear in peritoneal dialysis patients. In this study, we investigated the association between the distinct physical activity level or physical activity component and peritoneal dialysis clinical outcomes.
A total of 117 peritoneal dialysis patients who were admitted to the peritoneal dialysis clinic of Peking University Third Hospital from March to May 2008 were included in this study. Physical activity levels were assessed by the International Physical Activity Questionnaire (IPAQ). The associations between the physical activity behavior or its components and patients’ mortality were analyzed by Cox proportional hazards regression.
Wang, J., Nie, Jd., Tang, W. et al. Physical activity levels and mortality in peritoneal dialysis patients. BMC Nephrol 26, 694 (2025). https://doi.org/10.1186/s12882-025-04607-0
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