Intradialytic Exercise Improves Health Outcomes in Hemodialysis Patients

Patients with kidney failure undergoing chronic hemodialysis (HD) often grapple with imbalances in mineral metabolism and disruptions in cardiovascular and skeletal health, contributing to a higher mortality rate. However, a recent study conducted in an HD center in Iran suggests that intradialytic exercise could be a game-changer in regulating these abnormalities and improving patient well-being.

The randomized controlled trial, which spanned 6 months, divided 44 adult patients receiving chronic HD into two groups: an intervention group, where participants engaged in 60 minutes of intradialytic exercise during the second hour of their thrice-weekly dialysis sessions, and a control group that did not partake in any intradialytic exercise.

The primary focus of the study was on critical markers of mineral metabolism, including serum calcium, serum phosphorous, and parathyroid hormone levels. Secondary outcomes examined were serum alkaline phosphatase and the calcium-phosphorous product.

The findings of the study yielded promising results. Over the 6-month intervention period, significant differences emerged between the two groups across all primary and secondary outcomes. Notably, participants in the intradialytic exercise group experienced a statistically significant increase in serum calcium levels, while seeing significant decreases in serum phosphorous, parathyroid hormone, alkaline phosphatase, and the calcium-phosphorous product.