Monocyte-to-HDL-C Ratio Linked to Gout and Kidney Dysfunction Risk: Study
China: A new cross-sectional study published in Scientific Reports has found that the monocyte-to-HDL-C ratio (MHR) is significantly associated with an increased risk of gout and the severity of renal dysfunction. These associations were particularly notable in specific subgroups, including males, Mexican Americans, married individuals, those with insufficient physical activity, and people with diabetes. The findings highlight MHR as a potential marker for identifying at-risk individuals.
Gout, a prevalent form of inflammatory arthritis, is often linked to increased monocyte levels and decreased high-density lipoprotein cholesterol (HDL-C). Despite these known associations, the potential of the monocyte-to-HDL-C ratio (MHR) as a marker for gout risk has not been thoroughly examined.
To address this gap, Ke Xu, Tongji Shanxi Hospital, Shanxi Bethune Hospital, Shanxi Academy of Medical Sciences, Third Hospital of Shanxi Medical University, Taiyuan, China, and colleagues explore the relationship between MHR and the risk of developing gout, with a particular focus on cases complicated by renal dysfunction. The findings aim to offer a theoretical foundation that could support improved strategies for managing and preventing gout.
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