Osteoporosis Common Among Postmenopausal Lupus Nephritis Patients, Study Shows
China: A recent cross-sectional study conducted in China reveals a significant prevalence of osteoporosis among patients with lupus nephritis (LN), with postmenopausal individuals being particularly affected. This study sheds light on the critical risk factors associated with osteoporosis in this population, offering valuable insights for improved prevention and management strategies.
"We identified advanced age, lower body weight, and the lack of bisphosphonate treatment as key risk factors for osteoporosis in this patient population," the researchers wrote in BMC Nephrology.
Systemic lupus erythematosus (SLE) causes multisystemic damage, and lupus nephritis (LN) is a severe manifestation with significant health risks. Female SLE patients are at increased risk of reduced bone mineral density, osteoporosis, and fractures. The prevalence of osteoporosis in LN patients varies globally, with factors like glucocorticoid use and early menopause contributing to bone loss.
Against the above background, Yi Yang, Department of Nephrology, Tongji Hospital affiliated with Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China, and colleagues examined the prevalence of osteoporosis and identified risk factors contributing to the condition in both premenopausal and postmenopausal LN patients, highlighting the lack of data specific to the Chinese population. It aims to fill this gap by providing insights into the unique risk factors in this demographic.
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