Piroxicam and Paracetamol Ineffective in Preventing Renal Colic Recurrence: Study
A recent study published in the Academic Emergency Medicine revealed that common pain relievers, piroxicam and paracetamol, do not significantly reduce pain recurrence or prevent emergency department (ED) readmissions in patients treated for renal colic (RC). The study assessed the efficacy and safety of these medications in managing pain after patients were discharged from the ED.
This prospective, randomized, single-blind trial was conducted across four emergency departments. A total of 1,383 adults with RC were included in the study and were randomly assigned to receive either piroxicam, paracetamol, or a placebo for 5 days following their discharge from the ED. The primary focus was to determine if these medications could prevent pain recurrence and reduce the likelihood of patients returning to the ED within 7 days. Secondary outcomes included the time to pain recurrence and any side effects associated with the treatments.
The results indicated no significant differences in the efficacy of piroxicam or paracetamol when compared to the placebo in preventing pain recurrence. Pain recurrence within 7 days was observed in 29% of patients in the piroxicam group, 30.3% in the paracetamol group, and 30.8% in the placebo group. These figures suggest that the use of either piroxicam or paracetamol does not provide any substantial advantage in managing post-ED discharge pain for RC patients.
Disclaimer: This website is primarily for healthcare professionals. The content here does not replace medical advice and should not be used as medical, diagnostic, endorsement, treatment, or prescription advice. Medical science evolves rapidly, and we strive to keep our information current. If you find any discrepancies, please contact us at corrections@medicaldialogues.in. Read our Correction Policy here. Nothing here should be used as a substitute for medical advice, diagnosis, or treatment. We do not endorse any healthcare advice that contradicts a physician's guidance. Use of this site is subject to our Terms of Use, Privacy Policy, and Advertisement Policy. For more details, read our Full Disclaimer here.
NOTE: Join us in combating medical misinformation. If you encounter a questionable health, medical, or medical education claim, email us at factcheck@medicaldialogues.in for evaluation.