Sleep disorder and chronic kidney disease may have Bidirectional association, unravels study
A new meta-analysis published in the recent issue of Clinical Kidney Journal revealed a significant bidirectional relationship between chronic kidney disease (CKD) and various sleep disorders, including obstructive sleep apnea (OSA), restless leg syndrome (RLS), and insomnia. The study utilized data from over 26 million patients on the interplay between these health conditions and highlighted the potential for targeted interventions to improve patient outcomes. By addressing sleep disorders, physicians may reduce the progression of CKD and improve the quality of life for the ones affected.
This research reviewed 63 observational studies following a systematic protocol registered on PROSPERO. After analyzing data from major medical databases like Medline/PubMed, Embase, Cochrane Library, and CINAHL. The risk ratios (RRs) were calculated to quantify the associations between CKD and sleep disorders.
The outcomes of this study found that obstructive sleep apnea (OSA) was significantly linked to CKD, with a 68% higher risk for CKD development among individuals with OSA (RR 1.68; 95% CI 1.45–1.93). The patients with CKD underwent a 60% higher risk of developing OSA (RR 1.60; 95% CI 1.35–1.89).
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