Strict Phosphate Control Delays CAC Progression In Patients On Hemodialysis, EPISODE Trial
Written By : Dr Kartikeya Kohli
Medically Reviewed By : Dr. Kamal Kant Kohli
Published On 2021-04-18 18:00 GMT | Update On 2021-04-19 04:53 GMT
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In patients on maintenance dialysis, cardiovascular mortality risk is remarkably high, which can be partly explained by severe coronary artery calcification (CAC). In a study, strict phosphate control shows promise for delaying CAC progression in patients on hemodialysis. The study findings were published in the Journal of the American Society of Nephrology on February 26, 2021.
Hyperphosphatemia has been reported to be associated with the severity of CAC. However, the optimal phosphate range in patients on dialysis remains unknown. Therefore, Yoshitaka Isaka and his team conducted a study to compare the effects on CAC progression of two types of noncalcium-based phosphate binders and of two different phosphate target ranges.
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