intravenous cangrelor beneficial for acute ischemic stroke:Study
A small dose of intravenous cangrelor is as good as oral antiplatelets in acute ischemic stroke, suggests a study published in the Frontiers of Neurology.
Neuro-interventional procedures in acute ischemic stroke often require immediate antiplatelet therapy in the cases of acute stenting and occasionally re-occluding vessels. Intravenous cangrelor is a P2Y12 receptor antagonist with a short onset and quick offset.
A study was conducted by a group of researchers from the U.S.A. to evaluate the safety and efficacy of intravenous cangrelor in patients with acute ischemic stroke requiring urgent antiplatelet effect.
Patients who received intravenous cangrelor intra-procedurally during acute ischemic stroke treatment were identified from a prospectively collected database. Cangrelor was administered as a bolus of 15 mcg/kg, followed by an infusion rate of 2 mcg/kg/min. A historical control group consisting of anterior circulation tandem occlusions was used to compare to patients with similar lesions who received intravenous cangrelor.
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