Hyderabad lab makes stride in JE virus using cost-effective biosensor

New Delhi: In a major development towards the battle of the menace of Japenese Encephalitis in the country, a hyderabad based company has developed a less hazardous biosensor.

The National Institute of Animal Biotechnology (NIAB), Hyderabad has developed a cost-effective and relatively less hazardous biosensor for detecting Japanese Encephalitis Virus (JEV), an official statement said on Thursday.

The NIAB has developed Fluorine Doped Tin Oxide (FTO) electrode fabricated with reduced Graphene Oxide (rGO) as an electrochemical-based immune-sensor for the rapid, sensitive and specific detection of the Non-Structural 1 (NS1) secretory protein, which in turn, is suitable biomarker for JEV found circulating in the blood and has been reported to elicit an immune response, the Science and Technology Ministry statement said.

"Since the conventional methods for JEV diagnosis are expensive, more hazardous and time-consuming diagnostic techniques and require an elaborate laboratory set up and trained expertise, this biosensor may be able to overcome these limitations," it said.

The JEV is the leading cause of mosquito-borne encephalitis in South-East Asia and Western Pacific and is often misdiagnosed as dengue. JEV belongs to the family Flaviviridae and genus Flavivirus and exists in a zoonotic cycle. Since there is no cure available for JEV, early detection is essential to mitigate a breakout.