UK study to test Pfizer COVID drug Paxlovid in hospitalised patients
Recovery, led by the University of Oxford, will probe whether Paxlovid shortens the length of hospital stay or reduces the need for a mechanical ventilator, they added.;
New Delhi: Pfizer's oral COVID-19 therapy will be evaluated as a potential treatment for patients hospitalised with the illness in a major British trial, scientists said on Monday, as cases rise in some parts of the world.
The world's largest randomised study of potential medicines for COVID-19, dubbed the RECOVERY trial, will assess Paxlovid across hospitals in Britain, which has already approved the drug for early-stage treatment.
RECOVERY, led by the University of Oxford, will also probe whether Paxlovid shortens the length of hospital stay or reduces the need for a mechanical ventilator, they added.
Paxlovid is part of a class of drugs called protease inhibitors, currently used to treat HIV, hepatitis C as well as other viruses, and works by stopping the virus from replicating.
Pfizer, which is now testing Paxlovid for use in children, has said it expects more than $20 billion in sales from Paxlovid this year.
Scientists behind the RECOVERY trial in 2020 showed that dexamethasone, a steroid, was able to save the lives of patients in a "major breakthrough" in the pandemic. They also discovered the effectiveness of treatments such as arthritis drug tocilizumab and antibody cocktail Ronapreve.
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