Hysteroscopic diagnostic criteria precise in detecting chronic endometritis: Study
A new study published in the American Journal of Obstetrics and Gynecology found the hysteroscopic diagnostic criteria to be highly sensitive and reliable for identifying chronic endometritis.
Chronic endometritis (CE) is characterized by ongoing inflammation of the uterine mucosa. The microscopic detection of plasma cells in the endometrial stroma is a characteristic of this disease. Although few cases of abacterial CE have been reported, several bacteria, mostly gram-negative and intracellular (including Enterococcus faecalis, Escherichia coli, urea-plasma, Mycoplasma, Chlamydia, and Streptococcus spp.), have been linked to the development of CE.
The gold standard method for diagnosing and treating endocervical and intracavitary lesions is hysteroscopy. Thus, to evaluate the diagnostic accuracy of current hysteroscopic criteria in comparison to histological examination (with or without supplementary immunohistochemistry) for the diagnosis of chronic endometritis, Gaetano Riemma and colleagues carried out this study.
The diagnostic accuracy of hysteroscopy for chronic endometritis was assessed by comparing hysteroscopic criteria with histological (with or without immunohistochemistry) diagnosis. Studies were chosen based on whether they were prospective, retrospective, or randomized. The diagnostic odds ratio, sensitivity, specificity, and area under the summary receiver operating characteristic curve were the main results. Secondary outcomes included both positive and negative probability ratios.
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