SSRIs use at delivery may increase risk of postpartum hemorrhage in dose dependent manner: Study
Depression during pregnancy poses significant risks to both maternal and fetal health, including an increased risk of suicide and adverse newborn outcomes. While selective serotonin re-uptake inhibitors (SSRIs) are effective in treating depression, their use during pregnancy has been associated with bleeding complications at delivery. A recent study investigated the relationship between SSRIs and bleeding complications during delivery among pregnant women.
This study was published in the European Journal of Obstetrics Gynecology and Reproductive Biology by Malin O. and colleagues. A hospital-based cohort study was conducted at Karolinska University Hospital in Stockholm over a 5-year period from 2007 to 2011. The study included 334 women who delivered vaginally and were exposed to SSRIs at delivery, along with a control group of 31,929 women who delivered vaginally without SSRI exposure.
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