D- Dimer a safe diagnostic test to rule out VTE during pregnancy, finds study
Venous thromboembolism (VTE) is a leading cause of death and disability worldwide. The risk of VTE is higher in pregnant women and a leading cause of maternal death in western countries. A recent study by Marta Bellesini and their team evaluated the safety of D- Dimer as a diagnostic tool in pregnant women. The study is published in the journal of thrombosis and hemostasis.
The objective of the study was to investigate the safety of D- Dimer as a diagnostic tool in pregnant women to rule out VTE with suspected pulmonary embolism and deep vein thrombosis.
The study had two reviewers independently identify studies through PubMed and Embase until the first week of June 2021. They strengthened the study by manually reviewing reference lists of all retrieved articles, clinicalTrials.gov, and reference literature. Prospective or retrospective studies in which a formal diagnostic algorithm was used to evaluate the ability of D-dimer to rule out VTE during pregnancy were considered eligible.
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