Antiemetic fosnetupitant safe in breast cancer patients receiving AC/EC: study
Fosnetupitant (FosNTP) demonstrated favourable safety as Anti-emetic for breast cancer patients receiving chemotherapy, according to a recent study published in journal cancer.
A previous phase 2 study had shown a favourable safety profile and antiemetic activity of FosNTP in patients receiving cisplatin-based chemotherapy.
Breast cancer can occur in women and rarely in men. Symptoms of breast cancer include a lump in the breast, bloody discharge from the nipple and changes in the shape or texture of the nipple or breast. Its treatment depends on the stage of cancer. It may consist of chemotherapy, radiation, hormone therapy and surgery.
Advances in screening and treatment for breast cancer have improved survival rates dramatically. Overall, the rate of breast cancer declined by about 40%Trusted Source between 1989 and 2017. A 2019 study showed, however, that the rate in the United States may no longer be declining in women aged 20–39 years.
In the randomized, double-blind, multicenter, phase 3, CONSOLE-BC trial, 102 patients with breast cancer treated with AC/EC chemotherapy were randomly assigned to receive either FosNTP or fosaprepitant (FosAPR), both in combination with intravenous palonosetron and dexamethasone.
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