Continuous lavage with voriconazole CONTROLS progression in moderate and severe fungal keratitis
The study entitled "Continuous voriconazole lavage in managing moderate and severe fungal keratitis: a randomized controlled trial" by Gong et and the team has described the role of continuous lavage with voriconazole in controlling the progression of moderate and severe fungal keratitis. It does not cause damage to the corneal epithelium, stroma or conjunctiva.
This study is published in Graefe's Archive for Clinical and Experimental Ophthalmology.
It is already known that continuous lavage with antibiotics is proven to be SUCCESSFUL for managing resistant bacterial keratitis. This is because it increases the drug concentration in the cornea.
The main purpose of this study was to assess the effectiveness and safety of continuous lavage with 1% voriconazole (CL) for moderate and severe fungal keratitis.
The researchers randomized thirty-one patients receiving topical eye drops either alone (T) or combined with continuous 1% voriconazole lavage (CL-T) and measured the cure rate at three months as the primary outcomes.
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