Ring Amplitude and its effects on Diabetic eyes - A Multifocal electro retinography study

New research published in the journal "Seminars in Ophthalmology,2022" found that diabetes affects the central rings more than the peripheral rings and the effects are unevenly distributed on the retinal topography. 

Diabetic Retinopathy is an ocular complication of diabetes, a metabolic disorder affecting a huge population worldwide. If left untreated this disease can reduce vision leading to blindness. Researchers from Turkey conducted a study to evaluate the ring amplitudes in diabetic patients, the effect of the risk factors for diabetic retinopathy on the ring amplitudes, and the success of ring amplitudes in classifying diabetic retinopathy. 

The study included 32 eyes of 32 diabetic patients without retinopathy (DM), 34 eyes of 34 patients with mild non-proliferative diabetic retinopathy (NPDR) without macular edema, and 62 eyes of 62 age- and sex-matched controls (CG). Evaluation of all the patients was done using Multifocal Electroretinography (mfERG). Parameters like the relationship between age, diabetes duration, HbA1c and ring amplitudes, and the effect of diabetes and hypertension on ring amplitudes were evaluated. The discrimination power of the ring amplitudes was evaluated by a three-way ROC analysis.