Elevated blood lead levels may raise osteoporosis risk in women.
Osteoporosis is characterized by bone mass loss and bone microstructure degeneration, making bones fragile and brittle with a higher risk of fractures. Risk factors for osteoporosis can be modifiable and non-modifiable. A lack of essential minerals like calcium and magnesium can contribute to osteoporosis development. Studies have shown that trace elements are essential for bone growth and metabolism, but their specific roles in osteoporosis are poorly understood.
A study published in the Journal of Orthopaedic Surgery and Research revealed that higher blood lead levels are related to reduced bone density in women's lumbar spine, pelvis, and total femur. On the other hand, increased blood selenium levels are associated with increased bone density in the pelvis. No association was found for other trace elements such as iron, zinc, copper, manganese, cadmium, or mercury. Researchers also suggested that elevated blood lead levels may raise osteoporosis risk in women, while other trace elements do not have such an effect.
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