Osteoporosis Tied to Higher Depression Risk in Older Adults

Osteoporosis, a prevalent form of arthritis worldwide, is characterized by low bone mass and bone tissue deterioration. It affects approximately 14.8% of the global population older than 30, as per a 2023 study. Beyond the well-known risk of fractures, this research explores the potential link between osteoporosis and depressive symptoms in older individuals.

The cross-sectional study analyzed data from the US National Health and Nutrition Examination Survey (NHANES) spanning multiple years. Bone mineral density diagnoses were determined by dual-energy X-ray absorptiometry, while depression symptoms were assessed using the Patient Health Questionnaire-9. The study encompassed 11,603 adults aged 50 and above.

Key Findings:

• Individuals with osteoporosis had a 73% higher risk of experiencing depression symptoms compared to those without osteoporosis.

• Of the participants with osteoporosis, 31.9% exhibited depressive symptoms, and 10% had probable depression.

• Adjusted for various factors, individuals with osteoporosis were 1.73 times more likely to experience depressive symptoms and 1.91 times more likely to experience probable depression.

• The study suggests potential explanations, including the impact of bone mass loss on fractures, comorbidities, and financial burdens leading to avoidance of physical activity.

The study underscores the importance of closely monitoring the mental well-being of osteoporosis patients in both clinical and primary health care settings. While acknowledging the limitations of a cross-sectional design, the findings provide valuable insights into the intricate relationship between osteoporosis and depression in older adults.

Reference:

Chen K, Wang T, Tong X, et al. Osteoporosis is associated with depression among older adults: a nationwide population-based study in the USA from 2005 to 2020. Public Health. 2024;226:27-31. doi:10.1016/j.puhe.2023.10.022