PCOS tied to knee osteoarthritis impairing daily living activities: Study
According to recent research, it has been observed that women with polycystic ovary syndrome (PCOS) may experience knee-related symptoms and impaired activities of daily living (ADL), as published in the Journal of Clinical Rheumatology.
Plamena Kabakchieva and colleagues from the Clinic of Endocrinology, University Hospital "Alexandrovska", Department of Internal Medicine, Medical Faculty, Medical University of Sofia, Bulgaria carried out the study with the objective to analyze the link between hyperandrogenism and early clinical manifestations of osteoarthritis (OA), knee cartilage thickness, and serum cartilage oligomeric matrix protein (sCOMP) levels in patients with polycystic ovary syndrome (PCOS) and to compare them with healthy volunteers.
The researchers included a total of fifty-four PCOS patients, all of whom met the Rotterdam criteria with phenotypes A, B, and C. They were compared with 26 age- and body mass index (BMI)-matched controls. Detailed anthropometric measurements and clinical evaluation for hyperandrogenism were performed for all participants who also filled in the Knee Injury and Osteoarthritis Outcome Score (KOOS) questionnaire.
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