Upadacitinib bests abracept in tough Rheumatoid Arthritis Cases: NEJM study
Upadacitinib is an oral selective Janus kinase inhibitor to treat rheumatoid arthritis. The efficacy and safety of upadacitinib as compared with abatacept, a T-cell costimulation modulator, in patients with rheumatoid arthritis refractory to biologic disease-modifying antirheumatic drugs (DMARDs) are unclear.
Researchers have found in a new clinical trial that a recently approved rheumatoid arthritis medication Upadacitinib appears to be an effective second-line therapy when biologic treatments start to fail. Further Upadacitinib was found abracept in tough Rheumatoid Arthritis Cases.
Upadacitinib marketed under the brand name Rinvoq, has helped twice as many patients achieve remission from their rheumatoid arthritis state, according to a report in the New England Journal of Medicine.
Upadacitinib belongs in a class of drugs called Janus kinase (JAK) inhibitors, which also treat rheumatoid arthritis symptoms by manipulating the immune system.It received it approval from the U.S. Food and Drug Administration in August 2019 for treatment of moderate to severe rheumatoid arthritis.
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