Prenatal Opioid Exposure tied to Asthma development in Children, finds study
According to a recent study, children exposed to Prenatal Opioid were more likely to be diagnosed with asthma by 8 years of age than infants in the healthy control group.
The study, "Increased Incidence of Asthma in Children with Prenatal Opioid Exposure", was published online at The University of New Mexico Digital Repository.
Prenatal opioid exposure (POE) has increased dramatically in the last 10 years, with nearly 100 babies born daily in the United States with Neonatal Opioid Withdrawal Syndrome (NOWS). The impact on long-term outcomes continues to be investigated.
Given the proinflammatory state that results from POE, the research team hypothesized that infants with POE or NOWS diagnoses during the newborn hospitalization would have an altered immune reactivity that persisted into childhood, defined by asthma diagnosis within the first 8 years.
With this background, Isabella Cervantes et al, at the University of New Mexico School of Medicine, Albuquerque, designed a retrospective cohort design utilizing a comprehensive CERNER HealthFacts U.S. national database, which accesses clinical data from 800 hospitals across the country. ICD-9-CM and ICD-10-CM diagnosis codes were used to identify infants born at term with known POE or NOWS and were compared to healthy control infants with no diagnoses at birth other than normal newborn codes. The incidence of asthma during the first 8 years of life was determined.
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