Delayed antibiotics reduce adverse GI effects in kids with respiratory infections: Study
Spain: Children with uncomplicated respiratory tract infections (RTIs) who received delayed antibiotic prescription (DAP) had reduced gastrointestinal adverse effects and less antibiotic use versus those who received immediate antibiotic prescription (IAP), finds recent study. The study is published in the AAP journal Pediatrics.
However, there was no significant difference in symptom severity or duration in children who received DAP compared to no antibiotic prescription (NAP) or IAP strategies.
Gemma Mas-Dalmau, Biomedical Research Institute Sant Pau (IIB Sant Pau), Barcelona, Spain, and colleagues aimed to assess safety and effectiveness of DAP compared to IAP and NAP in children with uncomplicated respiratory infections.
For the purpose, the researchers performed a randomized clinical trial that compared 3 antibiotic prescription strategies. It included 436 children with acute uncomplicated respiratory infections attended to in 39 primary care centers.
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