Probiotics use reduces morbidity and mortality in premature infants: Study
Preterm birth is a major determinant of neonatal survival and morbidity, but, the gut microbiome and associated enteric inflammation are also key factors in neonatal development and the risk of associated morbidities. Recent research findings suggest that Bifidobacterium longum subsp. infantis (activated B. infantis EVC001) use in a NICU setting has improved the clinical, physiological, and microbiome-associated outcomes in preterm infants. The research has been published in the journal Frontiers in Pediatrics on February 16, 2021.
In animal models, B. infantis supplementation effectively reduced the necrotizing enterocolitis (NEC) injury scores and minimized intestinal inflammation. A recent observational study comparing longitudinal fecal samples taken from preterm infants showed that supplementation with Bifidobacterium and Lactobacillus remodelled the gut microbiome, replicating a gut microbiome more closely resembling that of a term infant. However, the physiological effects on the host were not determined. Researchers of the USA conducted a study to examine the effect of feeding B. infantis EVC001 to a preterm infant population.
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